Prof Dr. Powles is the lead for solid tumor research at Barts Cancer Institute (BCI) and also leads the genitourinary (GU) cancer group at BCI and a Trustee of Kidney Cancer UK.
His work focuses on a spectrum of clinical studies from phase I to randomised phase III. The majority of the studies are translational phase II studies investigating novel targeted and immune therapies. They exploit functional imaging and tissue collection. Alongside these trials, his team’s research focuses on correlation of novel biomarkers and aims to define markers that are of prognostic value and can predict response or resistance to therapy. Prof Powles has written over 100 peer review papers in this area. He is on the editorial board of a number of journals and is part of the faculty for the major global oncology meetings.